A leap in joint care science.

Fast-acting Rejensa® joint care chews are clinically proven to deliver a visible difference in as little as 16 days*.

Rejensa products

Rejenerating joint care science

Innovative molecule = Innovative joint supplement

You’ve seen it happen. As dogs mature, joint health issues and osteoarthritis can have a huge impact on their quality of life.

Rejensa container

Rejensa

About Rejensa

Rejensa is the only joint care supplement for dogs that contains N-Butyryl Glucosamine (GlcNBu), or Gluco Blu® (N-Butyryl Glucosamine) – an improved form of glucosamine clinically proven to deliver a visible difference in as little as 16 days with daily use.

Make Rejensa part of your multimodal approach to joint care and mobility.

What is Gluco Blu?

Rejensa

  • Gluco Blu (N-Butyryl Glucosamine) is a breakthrough analog of glucosamine awarded a US Patent.
  • This innovative molecule’s purpose is to enhance cartilage formation, chondrocyte cell proliferation and production of glycosaminoglycan, which impact the symptoms of joint stiffness and restricted mobility in dogs.
Regular Glucosamine

Regular glucosamine

N-Butyryl Glucosamine

Rejensa (N-Butyryl Glucosamine)

The once-a-day chew that can make a difference.

A highly palatable chew designed to be given to dogs daily. Rejensa with Gluco Blu can be given at any time as a stand-alone supplement for joint health. Also, we have no reports of adverse events when taken with prescribed joint medications – but as always we recommend that the pet owner consult with you, their veterinarian, on all of their pet healthcare needs.

Dosing chart

Dog’s weight Number of chews
per day
Days given
30-chew jar
Days given
60-chew jar
Up to 29 lbs ½ 60 Days 120 Days
30 to 59 lbs 1 30 Days 60 Days
60 to 89 lbs 1 ½ 20 Days 40 Days
90 to 120 lbs 2 15 Days 30 Days

Each chew contains: N-Butyryl Glucosamine (Gluco Blu) 1,620 mg

Other ingredients: Caramel Powder, Chicken Digest, Chicken Meal, Cultured Skim Milk, Dried Molasses, Egg Product, Glycerin, Natural Smoke Flavor, Rice Flour, Rice Bran, Salt, Tocopherol (as a preservative). Ingredients listed in alphabetical order.

Featured studies

Assessment of the Effectiveness of GLcNBu as a Therapeutic for Osteoarthritis in the Beagle Dog – CanCog

Summary: Clinical trials measuring mobility showed that Rejensa with Gluco Blu:

  • Achieved statistical significance on improving mobility with results equal to a leading prescription nonsteroidal anti-inflammatory drug (NSAID) – without the concerns of NSAID use; and
  • Achieved statistical superiority versus a leading non-prescription joint supplement.

Assessment of the Effectiveness of GlcNBu as a Therapeutic for Osteoarthritis in the Beagle Dog – Vivocore Inc.

Summary: Clinical tests measuring mobility and Quality Of Life (QOL) showed that Rejensa with Gluco Blu achieved statistical significance on improving mobility with results equal to a leading prescription nonsteroidal anti-inflammatory drug (NSAID) – Carprofen – without the concerns of NSAID use.

N-Butyryl Glucosamine Increases Matrix Gene Expression by Chondrocytes

Summary: Extending the alkyl chain of glucosamine (GlcN) produced an analog that enhances the expression of cartilage matrix genes by chondrocytes. GlcNBu alone increased the levels of type II collagen and aggrecan mRNA and helped chondrocytes to offset the shutdown of type II collagen gene expression induced by tumor necrosis factor-α (TNFα). Promoting expression of these two key extracellular molecules and preventing chondrocyte dedifferentiation is critical for preserving cartilage tissue and promoting its repair at times of injury.

N-Acylation of Glucosamine Modulates Chondrocyte Growth, Proteoglycan Synthesis, and Gene Expression

Summary: Addition of N-Butyryl Glucosamine (GlcNBu) to Bovine Articular Chondrocyte (BAC) or Human Articular Chondrocyte (HAC) to anchorage-dependent (AD) cultures generally stimulated cell proliferation and proteoglyan (PG) synthesis, while addition of glucosamine (GlcN) resulted in inhibition of these indicators. The inhibitory effects of the GlcN molecule appear to be related to the unsubstituted amino group. Additions of GlcNBu, but not GlcN, to HAC resulted in upregulation in the expression of a large number of genes.

Disease Modifying Effects of N-Butyryl Glucosamine in a Streptococcal Cell Wall Induced Arthritis Model in Rats

Summary: This data indicates that N-Butyryl Glucosamine (GlcNBu) provides anti-inflammatory and antierosive effects by preserving bone mineral density (BMD), joint integrity, and bone architecture in involved joints of the Streptococcal Cell Wall (SCW) model.

N-Acylated Glucosamines for Bone and Joint Disorders: Effects of N-Butyryl Glucosamine on Ovariectomized Rat Bone

Summary: We conclude that N-Butyryl Glucosamine (GlcNBu) feeding in the overiectomized (OVX) rat preserves bone mineral and some biomechanical properties. Translationally, GlcNBu can be positioned between nutriceuticals and pharmaceuticals for the prevention and treatment of osteoporosis.

Digital assets

Easy-to-use digital marketing assets will bring clients into your clinic. Below, you will find downloadable email assets (simply select the format that works best for you) as well as social media assets that you can use to invite clients to your clinic for their FREE Starter Pack of Rejensa.

icon - email

Email**

Supplied email copy and image

Send an email through your practice management system using the pre-written copy and image.

Download Assets

HTML email template

Send an email through your practice management system using this HTML template.

Download Assets
icon - social

Social

Supplied social media assets

Use the prepared text and image to post Rejensa content to your clinic’s social media page.

Download Assets

FAQs

FAQ first column

Rejensa joint care chews are a clinically proven daily supplement to support canine joint health with the innovative molecule Gluco Blu (N-Butyryl Glucosamine). They come in a delicious, soft chew that dogs will love.

Rejensa has been clinically proven to deliver a visible difference in dogs in as little as 16 days – with no loading dose.

In a blinded crossover study that evaluated quality of life, dogs given Rejensa with Gluco Blu for 16 days improved significantly, while those given a leading glucosamine chondroitin product did not.

Quality-of-life parameters measured included a number of mobility assessments:

  • Climbing the stairs
  • Jumping up and down
  • Walking and running
  • Jumping over low obstacles
  • General activity levels

Gluco Blu is N-Butyryl Glucosamine (GlcNBu), a breakthrough analog of glucosamine developed as an improved form to provide clinical benefits. Rejensa is the only joint care chew on the market today that contains this revolutionary, clinically proven form of glucosamine.

Rejensa is available in two jar sizes: 30 chews and 60 chews.

Each chew contains:
N-Butyryl Glucosamine (Gluco Blu) . . . . . . 1,620 mg

Other ingredients: Caramel Powder, Chicken Digest, Chicken Meal, Cultured Skim Milk, Dried Molasses, Egg Product, Glycerin, Natural Smoke Flavor, Rice Flour, Rice Bran, Salt, Tocopherol (as a preservative).

Ingredients are listed in alphabetical order.

FAQ second column

Clients should see a visible difference in their dogs in as little as 16 days* when Rejensa is given daily. Since the severity of joint pain can vary from dog to dog, results may vary.

Dog’s weight Number of chews
per day
Days given
30-chew jar
Days given
60-chew jar
Up to 29 lbs ½ 60 Days 120 Days
30 to 59 lbs 1 30 Days 60 Days
60 to 89 lbs 1 ½ 20 Days 40 Days
90 to 120 lbs 2 15 Days 30 Days

A daily treatment of Rejensa is designed to help manage the battle of joint stiffness and restricted mobility in dogs and works alongside appropriate exercise and fitness regimens, diet and weight management plans, and other pain relief therapies as an integral part of an overall, multimodal plan.

Generally, published literature recommends dogs should be treated with joint supplements on a case-by-case basis, with some literature recommending administering to at-risk breeds as early as when they are weaned and successfully on solid foods.

In the field, we have success stories of dogs of all ages, including puppies, having favorable outcomes while taking Rejensa.

Testimonials

Check out the great things people are saying about Rejensa!

Dr. Zack Mills

Dr. Zack Mills, Practice Owner, GA

After reading the clinical studies I decided to give Rejensa a try on a few dogs that suffered with joint pain.

I was impressed with the efficacy as it delivered what it said it would: results within 16 days. It is the most remarkable new product I have tried in a long time.

I am very happy with this veterinarian-exclusive product and the assistance the company has given me to regain my clients that were lost to online pharmacy!

Rambo

Dr. Jeff Van Petten, KS

Rambo is our 12-year-old pointer who has lived with our son for the past 3 years.

This past March he brought her home and she was not weight-bearing on her back-right leg.

On physical examination, it was easily determined that she had arthritis on both stifle joints. X-rays showed severe degenerative joint disease (DJD) of both stifles.

She received an acupuncture treatment and was started on a leading NSAID, a canine muscle formula, and Rejensa.

After about 2 weeks, the NSAID was stopped and she is doing much better. She’s running around like a puppy.

Brinley

Dr. Chris Sevigny, ME

My personal dog, Brinley, is a very old, arthritic girl. She is 15 and spent her first 12 or 13 years treating her body like an NFL linebacker. She was on an NSAID prior to starting on Rejensa, so I took Brinley off the NSAIDs for 2 weeks to wash them out of her system. We noticed a significant decline in her comfort, activity, and “speed of movement.”

After a few weeks on just the Rejensa, we did notice a genuine improvement in each of those categories. I did eventually put her back on NSAIDs in addition to the Rejensa, simply to maximize her comfort in her golden years, but she has maintained an improved mobility and quality of life greater than when using either of them alone.

I use my own experience with Rejensa when discussing treatment options with my clients. The Starter Packs have made a huge difference when starting a new client on the product as well. We also appreciate the larger tubs for the bigger dogs. Our overall impression from clients has been greatly positive.

We are recommending it across the board for dogs we think need improved joint health. Old dogs with degenerative joint disease (DJD) are still probably our #1 group, but we add it for animals with demonstrated joint injuries like CCL tears or luxating patellas. We are recommending it in earlier cases as a single treatment before we initiate NSAIDs, or after a short course of NSAIDs to relieve more acute pain.

We have also found it to be consistently palatable, even for some of our pickier patients.

I am a big fan of Rejensa, as is our staff!

Dr. George Cattiny

Dr. George Cattiny, NJ

Rejensa is the best new mobility product for dogs I have seen in the last 10-15 years.

Dr. Cecilia Fisher

Dr. Cecilia Fisher, FL

I am so excited I could jump like dogs on Rejensa!

Dr. Lance Kidder

Dr. Lance Kidder, NV

I was skeptical at first, but after seeing my associate’s positive results with her own dog, along with numerous patients with similar mobility improvements, it took no more convincing.

Rejensa is the supplement I recommend when treating a wide range of patients with chronic lameness and arthritis.

Marissa Lucido

Marissa Lucido, VTIT, NV

Radiographs of my 1.5 year-old Pointer’s shoulder revealed an overgrowth of bone on the humerus was creating intermittent lameness and puts him at risk for arthritis sooner in his life.

We started him on Rejensa and the intermittent lameness hasn’t reared its ugly head since. Rejensa was definitely the right course of treatment for my boy.

Dr. Heidi Wendel

Dr. Heidi Wendel, NY

We are so happy to be able to offer Rejensa as our preferred joint supplement. We have seen amazing results in our senior patients and staff pets since transitioning to Rejensa!

Dr. Dani Cimino

Dr. Dani Cimino, MA

My staff and I have been very happy with Rejensa! This supplement has been helpful to many of our patients, including dogs that do not tolerate several products and others who are prone to joint injuries. We think Rejensa is a pro-active approach to managing our patients’ orthopedic health. There is no down-side to recommending Rejensa!

Dr. Sabrina Kordis

Dr. Sabrina Kordis, TX

Being a veterinarian, I have tried multiple joint supplements including Dasuquin, Cosequin, Dasuquin Advanced, Cadaflex and Phycox. None of these products have compared to the results I have seen from Rejensa in my own personal dogs or in my clients' dogs.

A year ago, I was facing the quality-of-life decision that all owners face and strongly considered humane euthanasia in my 15-year-old German Shepherd due to joint/mobility issues.

Within 7 days of starting Rejensa her mobility and energy levels had improved immensely. I am happy to report that she just celebrated her 16th birthday.

Dr. Justin Tran

Dr. Justin Tran, TX

We love Rejensa!

Why isn’t every vet clinic recommending it to all their canine joint care clients?

Articles

White paper:

New Rejensa™ Joint Care Chews. An Innovative Molecule Means an Innovative Approach to Joint Care.
By Lisa Dixon

Editorial:

Be Your Patient’s Hero. Get Ahead of Degenerative Joint Disease.
By Lisa Dixon

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